Cardiac Alterations’ New Imaging Signatures in Ischaemic Heart Disease and Cerebrovascular Disease Using CMR Radiomics
This study analysed cardiovascular magnetic resonance (CMR) images of UK Biobank’s subjects with pre-existing ischaemic heart disease (IHD), ischaemic cerebrovascular disease, myocardial infarction, and ischaemic stroke. Each disease group was compared with an equal number of healthy controls. The discriminatory power achieved by the radiomics signature was compared with conventional indices for each disease group, using the area under the curve (AUC), receiver operating characteristic (ROC) analysis, and paired t-test for statistical significance. A third model combining both radiomics and conventional indices was also evaluated. In all the study groups, radiomics signatures provided a significantly better disease discrimination than conventional indices, as suggested by AUC.